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The prevalence of depression in hereditary spastic paraplegia

Neurology Department, West-Tallinn Central Hospital, Tallinn and Institute of Psychology, University of Tallinn, Tallinn, liina.vahter{at}ltkh.ee

M. Braschinsky

Department of Neurology, Tartu University Clinics

S. Haldre

Department of Neurology, Tartu University Clinics

K. Gross-Paju

Neurology Department, West-Tallinn Central Hospital, Tallinn, Estonia

Objective: To evaluate the prevalence of depression and sensitivity and specificity of the single-item interview ‘Are you depressed?’ for people with hereditary spastic paraplegia in Estonia.

Design: Single-item interview ‘Are you depressed?’ was used as a screening question for depression; all participants then completed the Beck Depression Inventory.

Setting: People with hereditary spastic paraplegia identified from the epidemiological database who agreed to participate in the study.

Main measures: Beck Depression Inventory, clinical interview.

Results: The epidemiological database consisted of 59 patients with clinically confirmed diagnosis of hereditary spastic paraplegia. Forty-eight of these consented to participate in the study. The Beck Depression Inventory score was higher than cut-off point in 58% (28/48) and lower in 42% (20/48). Of the study group, 44% (21/48) had mild, 13% (6/48) moderate and one person revealed severe depression. There was a statistically significant correlation between Beck Depression Inventory score and level of mobility; no other significant correlations with other measures were detected. Of the participants, 54% (26/48) had subjective complaints about depression and answered ‘Yes’ to the single-item interview ‘Are you depressed?’. The sensitivity of the one-item interview in the hereditary spastic paraplegia group was 75% and specificity 75%.

Conclusions: Our results show that mild depression is prevalent among people with hereditary spastic paraplegia. Although the single question may be helpful, it cannot be relied upon entirely when assessing a person for depression.

This version was published on September 1, 2009

Clinical Rehabilitation, Vol. 23, No. 9, 857-861 (2009)
DOI: 10.1177/0269215509337186


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